Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise

BACKGROUND: Cell-to-cell variability in protein expression can be large, and its propagation through signaling networks affects biological outcomes. Here, we apply deterministic and probabilistic models and biochemical measurements to study how network topologies and cell-to-cell protein abundance v...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Birtwistle, Marc R, Rauch, Jens, Kiyatkin, Anatoly, Aksamitiene, Edita, Dobrzyński, Maciej, Hoek, Jan B, Kolch, Walter, Ogunnaike, Babatunde A, Kholodenko, Boris N
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484110/
https://ncbi.nlm.nih.gov/pubmed/22920937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-109
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