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Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise
BACKGROUND: Cell-to-cell variability in protein expression can be large, and its propagation through signaling networks affects biological outcomes. Here, we apply deterministic and probabilistic models and biochemical measurements to study how network topologies and cell-to-cell protein abundance v...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3484110/ https://ncbi.nlm.nih.gov/pubmed/22920937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-109 |
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