Prolactin-Stimulated Activation of ERK1/2 Mitogen-Activated Protein Kinases is Controlled by PI3-Kinase/Rac/PAK Signaling Pathway in Breast Cancer Cells

There is strong evidence that deregulation of prolactin (PRL) signaling contributes to pathogenesis and chemoresistance of breast cancer. Therefore, understanding cross-talk between distinct signal transduction pathways triggered by activation of the prolactin receptor (PRL-R), is essential for eluc...

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Bibliographische Detailangaben
Hauptverfasser: Aksamitiene, Edita, Achanta, Sirisha, Kolch, Walter, Kholodenko, Boris N., Hoek, Jan B., Kiyatkin, Anatoly
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156300/
https://ncbi.nlm.nih.gov/pubmed/21726627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.06.014
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