Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise

BACKGROUND: Cell-to-cell variability in protein expression can be large, and its propagation through signaling networks affects biological outcomes. Here, we apply deterministic and probabilistic models and biochemical measurements to study how network topologies and cell-to-cell protein abundance v...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Birtwistle, Marc R, Rauch, Jens, Kiyatkin, Anatoly, Aksamitiene, Edita, Dobrzyński, Maciej, Hoek, Jan B, Kolch, Walter, Ogunnaike, Babatunde A, Kholodenko, Boris N
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484110/
https://ncbi.nlm.nih.gov/pubmed/22920937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-109
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi