Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia

Expression of microRNAs (miRNAs) is under stringent regulation at both transcriptional and post-transcriptional levels. Disturbance at either level could cause dysregulation of miRNAs. Here we show that MLL fusion proteins negatively regulate production of miR-150, an miRNA widely repressed in acute...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jiang, Xi, Huang, Hao, Li, Zejuan, Li, Yuanyuan, Wang, Xiao, Gurbuxani, Sandeep, Chen, Ping, He, Chunjiang, You, Dewen, Zhang, Shuodan, Wang, Jinhua, Arnovitz, Stephen, Elkahloun, Abdel, Price, Colles, Hong, Gia-Ming, Ren, Haomin, Kunjamma, Rejani B., Neilly, Mary Beth, Matthews, Jono, Xu, Mengyi, Larson, Richard A., Le Beau, Michelle M., Slany, Robert K., Liu, Paul P., Lu, Jun, Zhang, Jiwang, He, Chuan, Chen, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480215/
https://ncbi.nlm.nih.gov/pubmed/23079661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.08.028
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados