TET1 plays an essential oncogenic role in MLL-rearranged leukemia

The ten-eleven translocation 1 (TET1) gene is the founding member of the TET family of enzymes (TET1/2/3) that convert 5-methylcytosine to 5-hydroxymethylcytosine. Although TET1 was first identified as a fusion partner of the mixed lineage leukemia (MLL) gene in acute myeloid leukemia carrying t(10,...

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Autori principali: Huang, Hao, Jiang, Xi, Li, Zejuan, Li, Yuanyuan, Song, Chun-Xiao, He, Chunjiang, Sun, Miao, Chen, Ping, Gurbuxani, Sandeep, Wang, Jiapeng, Hong, Gia-Ming, Elkahloun, Abdel G., Arnovitz, Stephen, Wang, Jinhua, Szulwach, Keith, Lin, Li, Street, Craig, Wunderlich, Mark, Dawlaty, Meelad, Neilly, Mary Beth, Jaenisch, Rudolf, Yang, Feng-Chun, Mulloy, James C., Jin, Peng, Liu, Paul P., Rowley, Janet D., Xu, Mingjiang, He, Chuan, Chen, Jianjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718141/
https://ncbi.nlm.nih.gov/pubmed/23818607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310656110
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