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Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia

Expression of functionally important genes is often tightly regulated at both transcriptional and post-transcriptional levels. We reported previously that TET1, the founding member of the TET methylcytosine dioxygenase family, plays an essential oncogenic role in MLL-rearranged acute myeloid leukemi...

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Podrobná bibliografie
Vydáno v:Cancer Lett
Hlavní autoři: Huang, Hao, Jiang, Xi, Wang, Jinhua, Li, Yuanyuan, Song, Chun-Xiao, Chen, Ping, Li, Shenglai, Gurbuxani, Sandeep, Arnovitz, Stephen, Wang, Yungui, Weng, Hengyou, Neilly, Mary Beth, He, Chuan, Li, Zejuan, Chen, Jianjun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809417/
https://ncbi.nlm.nih.gov/pubmed/26791235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.12.032
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