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Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia

HOXA9 plays a critical role in both normal hematopoiesis and leukemogenesis, particularly in the development and maintenance of mixed lineage leukemia (MLL)-rearranged leukemia. Through reverse transcription polymerase chain reaction (RT-PCR) analysis of HOXA9 transcripts in human leukemia and norma...

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Hlavní autoři: He, Miao, Chen, Ping, Arnovitz, Stephen, Li, Yuanyuan, Huang, Hao, Neilly, Mary Beth, Wei, Minjie, Rowley, Janet D., Chen, Jianjun, Li, Zejuan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399022/
https://ncbi.nlm.nih.gov/pubmed/22633751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2012.05.003
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