A major determinant of the immunogenicity of factor VIII in a murine model is independent of its procoagulant function

A main complication of treatment of patients with hemophilia A is the development of anti–factor VIII (fVIII) antibodies. The immunogenicity of fVIII potentially is a function of its procoagulant activity, which may result in danger signals that drive the immune response. Alternatively, intrinsic st...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Meeks, Shannon L., Cox, Courtney L., Healey, John F., Parker, Ernest T., Doshi, Bhavya S., Gangadharan, Bagirath, Barrow, Rachel T., Lollar, Pete
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448263/
https://ncbi.nlm.nih.gov/pubmed/22855607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-412361
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky