טוען...
A subset of high-titer anti–factor VIII A2 domain antibodies is responsive to treatment with factor VIII
The primary B-cell epitopes of factor VIII (fVIII) are in the A2 and C2 domains. Within the C2 domain, antibody epitope and kinetics are more important than inhibitor titer in predicting pathogenicity in a murine bleeding model. To investigate this within the A2 domain, the pathogenicity of a divers...
שמור ב:
| הוצא לאור ב: | Blood |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Hematology
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4841042/ https://ncbi.nlm.nih.gov/pubmed/26825708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-09-670034 |
| תגים: |
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