A major determinant of the immunogenicity of factor VIII in a murine model is independent of its procoagulant function

Lignende værker

• Antihuman factor VIII C2 domain antibodies in hemophilia A mice recognize a functionally complex continuous spectrum of epitopes dominated by inhibitors of factor VIII activation
  af: Meeks, Shannon L., et al.
  Udgivet: (2007)
• Nonclassical anti-C2 domain antibodies are present in patients with factor VIII inhibitors
  af: Meeks, Shannon L., et al.
  Udgivet: (2008)
• The diversity of the immune response to the A2 domain of human factor VIII
  af: Markovitz, Rebecca C., et al.
  Udgivet: (2013)
• Non-Classical Anti-Factor VIII C2 Domain Antibodies Are Pathogenic in a Murine in vivo Bleeding Model
  af: Meeks, Shannon L., et al.
  Udgivet: (2009)
• A subset of high-titer anti–factor VIII A2 domain antibodies is responsive to treatment with factor VIII
  af: Eubanks, Joshua, et al.
  Udgivet: (2016)