Cks1 Promotion of S Phase Entry and Proliferation Is Independent of p27(Kip1) Suppression

Cks1 is an activator of the SCF(Skp2) ubiquitin ligase complex that targets the cell cycle inhibitor p27(Kip1) for degradation. The loss of Cks1 results in p27(Kip1) accumulation and decreased proliferation and inhibits tumorigenesis. We identify here a function of Cks1 in mammalian cell cycle regul...

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Detaylı Bibliyografya
Asıl Yazarlar: Hoellein, Alexander, Graf, Steffi, Bassermann, Florian, Schoeffmann, Stephanie, Platz, Ulrich, Hölzlwimmer, Gabriele, Kröger, Monika, Peschel, Christian, Oostendorp, Robert, Quintanilla-Fend, Leticia, Keller, Ulrich
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434501/
https://ncbi.nlm.nih.gov/pubmed/22508990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06771-11
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