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Sources of energy for gating by neurotransmitters in acetylcholine receptor channels

Nicotinic acetylcholine receptors (AChRs) mediate signaling in the central and peripheral nervous systems. The AChR gating conformational change is powered by a low- to high-affinity change for neurotransmitters at two transmitter binding sites. We estimated (from single-channel currents) the compon...

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Bibliografiske detaljer
Main Authors: Purohit, Prasad, Bruhova, Iva, Auerbach, Anthony
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386111/
https://ncbi.nlm.nih.gov/pubmed/22647603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203633109
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