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Unliganded gating of acetylcholine receptor channels
We estimated the unliganded opening and closing rate constants of neuromuscular acetylcholine receptor-channels (AChRs) having mutations that increased the gating equilibrium constant. For some mutant combinations, spontaneous openings occurred in clusters. For 25 different constructs, the unligande...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629231/ https://ncbi.nlm.nih.gov/pubmed/19114650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809272106 |
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