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Sources of energy for gating by neurotransmitters in acetylcholine receptor channels

Nicotinic acetylcholine receptors (AChRs) mediate signaling in the central and peripheral nervous systems. The AChR gating conformational change is powered by a low- to high-affinity change for neurotransmitters at two transmitter binding sites. We estimated (from single-channel currents) the compon...

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Hlavní autoři: Purohit, Prasad, Bruhova, Iva, Auerbach, Anthony
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386111/
https://ncbi.nlm.nih.gov/pubmed/22647603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203633109
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