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Sources of energy for gating by neurotransmitters in acetylcholine receptor channels

Nicotinic acetylcholine receptors (AChRs) mediate signaling in the central and peripheral nervous systems. The AChR gating conformational change is powered by a low- to high-affinity change for neurotransmitters at two transmitter binding sites. We estimated (from single-channel currents) the compon...

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Detalhes bibliográficos
Main Authors: Purohit, Prasad, Bruhova, Iva, Auerbach, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386111/
https://ncbi.nlm.nih.gov/pubmed/22647603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203633109
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