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Sources of energy for gating by neurotransmitters in acetylcholine receptor channels

Nicotinic acetylcholine receptors (AChRs) mediate signaling in the central and peripheral nervous systems. The AChR gating conformational change is powered by a low- to high-affinity change for neurotransmitters at two transmitter binding sites. We estimated (from single-channel currents) the compon...

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Bibliografiska uppgifter
Huvudupphovsmän: Purohit, Prasad, Bruhova, Iva, Auerbach, Anthony
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386111/
https://ncbi.nlm.nih.gov/pubmed/22647603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203633109
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