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Sources of energy for gating by neurotransmitters in acetylcholine receptor channels

Nicotinic acetylcholine receptors (AChRs) mediate signaling in the central and peripheral nervous systems. The AChR gating conformational change is powered by a low- to high-affinity change for neurotransmitters at two transmitter binding sites. We estimated (from single-channel currents) the compon...

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Bibliographic Details
Main Authors: Purohit, Prasad, Bruhova, Iva, Auerbach, Anthony
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386111/
https://ncbi.nlm.nih.gov/pubmed/22647603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203633109
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