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Loop C and the mechanism of acetylcholine receptor–channel gating
Agonist molecules at the two neuromuscular acetylcholine (ACh) receptor (AChR) transmitter-binding sites increase the probability of channel opening. In one hypothesis for AChR activation (“priming”), the capping of loop C at each binding site transfers energy independently to the distant gate over...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607824/ https://ncbi.nlm.nih.gov/pubmed/23478996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210946 |
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