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Modal affinities of endplate acetylcholine receptors caused by loop C mutations

The time course of the endplate current is determined by the rate and equilibrium constants for acetylcholine receptor (AChR) activation. We measured these constants in single-channel currents from AChRs with mutations at the neurotransmitter-binding sites, in loop C. The main findings are: (a) Almo...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Vij, Ridhima, Purohit, Prasad, Auerbach, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621750/
https://ncbi.nlm.nih.gov/pubmed/26503719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511503
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