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Cyclic activation of endplate acetylcholine receptors

Agonists turn on receptors because they have a higher affinity for active versus resting conformations of the protein. Activation can occur by either of two pathways that connect to form a cycle: Agonists bind to resting receptors that then become active, or resting receptors activate and then bind...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nayak, Tapan K., Auerbach, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692566/
https://ncbi.nlm.nih.gov/pubmed/29078356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711228114
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