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Functional differences between neurotransmitter binding sites of muscle acetylcholine receptors
A muscle acetylcholine receptor (AChR) has two neurotransmitter binding sites located in the extracellular domain, at αδ and either αε (adult) or αγ (fetal) subunit interfaces. We used single-channel electrophysiology to measure the effects of mutations of five conserved aromatic residues at each si...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267328/ https://ncbi.nlm.nih.gov/pubmed/25422413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414378111 |
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