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Catch-and-Hold Activation of Muscle Acetylcholine Receptors Having Transmitter Binding Site Mutations
Agonists turn on receptors because their target sites have a higher affinity in the active versus resting conformation of the protein. We used single-channel electrophysiology to measure the lower-affinity (LA) and higher-affinity (HA) equilibrium dissociation constants for acetylcholine in adult-ty...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119287/ https://ncbi.nlm.nih.gov/pubmed/24988344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.057 |
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