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Action of nicotine and analogs on acetylcholine receptors having mutations of transmitter-binding site residue αG153
A primary target for nicotine is the acetylcholine receptor channel (AChR). Some of the ability of nicotine to activate differentially AChR subtypes has been traced to a transmitter-binding site amino acid that is glycine in lower affinity and lysine in higher affinity AChRs. We studied the effects...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Rockefeller University Press
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536520/ https://ncbi.nlm.nih.gov/pubmed/23277476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210896 |
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