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Glycine Hinges with Opposing Actions at the Acetylcholine Receptor-Channel Transmitter Binding Site
The extent to which agonists activate synaptic receptor-channels depends on both the intrinsic tendency of the unliganded receptor to open and the amount of agonist binding energy realized in the channel-opening process. We examined mutations of the nicotinic acetylcholine receptor transmitter bindi...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061369/ https://ncbi.nlm.nih.gov/pubmed/21115636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.068767 |
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