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Function of Interfacial Prolines at the Transmitter-binding Sites of the Neuromuscular Acetylcholine Receptor

The neuromuscular acetylcholine (ACh) receptor has two conserved prolines in loop D of the complementary subunit at each of its two transmitter-binding sites (α-ϵ and α-δ). We used single-channel electrophysiology to estimate the energy changes caused by mutations of these prolines with regard to un...

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Detalhes bibliográficos
Main Authors: Gupta, Shaweta, Purohit, Prasad, Auerbach, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642313/
https://ncbi.nlm.nih.gov/pubmed/23519471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.443911
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