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Energetics of gating at the apo–acetylcholine receptor transmitter binding site
Acetylcholine receptor channels switch between conformations that have a low versus high affinity for the transmitter and conductance for ions (R↔R*; gating). The forward isomerization, which begins at the transmitter binding sites and propagates ∼50 Å to the narrow region of the pore, occurs by app...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Rockefeller University Press
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847916/ https://ncbi.nlm.nih.gov/pubmed/20351060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910384 |
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