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Functional differences between neurotransmitter binding sites of muscle acetylcholine receptors

A muscle acetylcholine receptor (AChR) has two neurotransmitter binding sites located in the extracellular domain, at αδ and either αε (adult) or αγ (fetal) subunit interfaces. We used single-channel electrophysiology to measure the effects of mutations of five conserved aromatic residues at each si...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Nayak, Tapan K., Bruhova, Iva, Chakraborty, Srirupa, Gupta, Shaweta, Zheng, Wenjun, Auerbach, Anthony
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267328/
https://ncbi.nlm.nih.gov/pubmed/25422413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414378111
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