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Energy and Structure of the M2 Helix in Acetylcholine Receptor-Channel Gating
We studied single-channel currents from neuromuscular acetylcholine receptor-channels with mutations in the pore-lining, M2 helix of the ɛ-subunit. Three parameters were quantified: 1), the diliganded gating equilibrium constant (E(2)), which reflects the energy difference between C(losed) and O(pen...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712209/ https://ncbi.nlm.nih.gov/pubmed/19450479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.02.030 |
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