Energy and Structure of the M2 Helix in Acetylcholine Receptor-Channel Gating

We studied single-channel currents from neuromuscular acetylcholine receptor-channels with mutations in the pore-lining, M2 helix of the ɛ-subunit. Three parameters were quantified: 1), the diliganded gating equilibrium constant (E(2)), which reflects the energy difference between C(losed) and O(pen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jha, Archana, Purohit, Prasad, Auerbach, Anthony
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2009
Gaiak:
Channels, Receptors, and Electrical Signaling
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712209/
https://ncbi.nlm.nih.gov/pubmed/19450479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.02.030
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