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Energy for Wild-Type Acetylcholine Receptor Channel Gating from Different Choline Derivatives
Agonists, including the neurotransmitter acetylcholine (ACh), bind at two sites in the neuromuscular ACh receptor channel (AChR) to promote a reversible, global change in protein conformation that regulates the flow of ions across the muscle cell membrane. In the synaptic cleft, ACh is hydrolyzed to...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Biophysical Society
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566445/ https://ncbi.nlm.nih.gov/pubmed/23442907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.11.3833 |
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