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Linking the Acetylcholine Receptor-Channel Agonist-Binding Sites with the Gate
The gating isomerization of neuromuscular acetylcholine receptors links the rearrangements of atoms at two transmitter-binding sites with those at a distant gate region in the pore. To explore the mechanism of this reversible process, we estimated the gating rate and equilibrium constants for recept...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913195/ https://ncbi.nlm.nih.gov/pubmed/20682257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.05.008 |
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