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Linking the Acetylcholine Receptor-Channel Agonist-Binding Sites with the Gate

The gating isomerization of neuromuscular acetylcholine receptors links the rearrangements of atoms at two transmitter-binding sites with those at a distant gate region in the pore. To explore the mechanism of this reversible process, we estimated the gating rate and equilibrium constants for recept...

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Detalles Bibliográficos
Autores principales: Cadugan, David J., Auerbach, Anthony
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913195/
https://ncbi.nlm.nih.gov/pubmed/20682257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.05.008
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