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Acetylcholine Receptor Channels Activated by a Single Agonist Molecule
The neuromuscular acetylcholine receptor (AChR) is an allosteric protein that alternatively adopts inactive versus active conformations (R↔R(∗)). The R(∗) shape has a higher agonist affinity and ionic conductance than R. To understand how agonists trigger this gating isomerization, we examined singl...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862204/ https://ncbi.nlm.nih.gov/pubmed/20441747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.01.025 |
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