Subunit Symmetry at the Extracellular Domain-Transmembrane Domain Interface in Acetylcholine Receptor Channel Gating

Transmitter molecules bind to synaptic acetylcholine receptor channels (AChRs) to promote a global channel-opening conformational change. Although the detailed mechanism that links ligand binding and channel gating is uncertain, the energy changes caused by mutations appear to be more symmetrical be...

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Detaylı Bibliyografya
Asıl Yazarlar: Bruhova, Iva, Auerbach, Anthony
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Molecular Biophysics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998135/
https://ncbi.nlm.nih.gov/pubmed/20864527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.169110
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