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Acetylcholine Receptor Gating at Extracellular Transmembrane Domain Interface: the “Pre-M1” Linker

Charged residues in the β10–M1 linker region (“pre-M1”) are important in the expression and function of neuromuscular acetylcholine receptors (AChRs). The perturbation of a salt bridge between pre-M1 residue R209 and loop 2 residue E45 has been proposed as being a principle event in the AChR gating...

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Detalles Bibliográficos
Main Authors: Purohit, Prasad, Auerbach, Anthony
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151659/
https://ncbi.nlm.nih.gov/pubmed/18040058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709857
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