Liver-Specific Loss of Atg5 Causes Persistent Activation of Nrf2 and Protects Against Acetaminophen-Induced Liver Injury

Autophagy is an evolutionarily conserved biological process that degrades intracellular proteins and organelles including damaged mitochondria through the formation of autophagosome. We have previously demonstrated that pharmacological induction of autophagy by rapamycin protects against acetaminoph...

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Detaylı Bibliyografya
Asıl Yazarlar: Ni, Hong-Min, Boggess, Nikki, McGill, Mitchell R., Lebofsky, Margitta, Borude, Prachi, Apte, Udayan, Jaeschke, Hartmut, Ding, Wen-Xing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Molecular Toxicology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355320/
https://ncbi.nlm.nih.gov/pubmed/22491424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs133
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