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DNA Damage Response Regulates Initiation of Liver Regeneration Following Acetaminophen Overdose

Acetaminophen (APAP) overdose is the leading cause of acute liver failure (ALF) with limited treatment options. It is known that liver regeneration following APAP-induced ALF is a deciding factor in the final outcome. Previous studies from our laboratory using an incremental dose model involving a r...

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Bibliographic Details
Published in:Gene Expr
Main Authors: Borude, Prachi, Bhushan, Bharat, Apte, Udayan
Format: Artigo
Language:Inglês
Published: Cognizant Communication Corporation 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954624/
https://ncbi.nlm.nih.gov/pubmed/29540258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221618X15205260749346
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