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DNA Damage Response Regulates Initiation of Liver Regeneration Following Acetaminophen Overdose

Acetaminophen (APAP) overdose is the leading cause of acute liver failure (ALF) with limited treatment options. It is known that liver regeneration following APAP-induced ALF is a deciding factor in the final outcome. Previous studies from our laboratory using an incremental dose model involving a r...

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Pubblicato in:Gene Expr
Autori principali: Borude, Prachi, Bhushan, Bharat, Apte, Udayan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cognizant Communication Corporation 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954624/
https://ncbi.nlm.nih.gov/pubmed/29540258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221618X15205260749346
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