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Liver-Specific Deletion of Integrin-Linked Kinase in Mice Attenuates Hepatotoxicity and Improves Liver Regeneration After Acetaminophen Overdose

Acetaminophen (APAP) overdose is the major cause of acute liver failure in the US. Prompt liver regeneration is critical for recovery after APAP hepatotoxicity, but mechanisms remain elusive. Extracellular matrix (ECM)-mediated signaling via integrin-linked kinase (ILK) regulates liver regeneration...

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Detalhes bibliográficos
Publicado no:Gene Expr
Main Authors: Bhushan, Bharat, Edwards, Genea, Desai, Aishwarya, Michalopoulos, George K., Apte, Udayan
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341619/
https://ncbi.nlm.nih.gov/pubmed/27125733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221616X691578
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