Role of Bile Acids in Liver Injury and Regeneration following Acetaminophen Overdose

Bile acids play a critical role in liver injury and regeneration, but their role in acetaminophen (APAP)–induced liver injury is not known. We tested the effect of bile acid modulation on APAP hepatotoxicity using C57BL/6 mice, which were fed a normal diet, a 2% cholestyramine (CSA)–containing diet...

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Detalhes bibliográficos
Main Authors: Bhushan, Bharat, Borude, Prachi, Edwards, Genea, Walesky, Chad, Cleveland, Joshua, Li, Feng, Ma, Xiaochao, Apte, Udayan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814573/
https://ncbi.nlm.nih.gov/pubmed/24007882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.07.012
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