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Pleiotropic Role of p53 in Injury and Liver Regeneration after Acetaminophen Overdose
p53 is the major cellular gatekeeper involved in proliferation, cell death, migration, and homeostasis. The role of p53 in pathogenesis of drug-induced liver injury is unknown. We investigated the role of p53 in liver injury and regeneration after acetaminophen (APAP) overdose, the most common cause...
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| Опубликовано в: : | Am J Pathol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Investigative Pathology
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5971235/ https://ncbi.nlm.nih.gov/pubmed/29654721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.03.006 |
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