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Liver Regeneration after Acetaminophen Hepatotoxicity: Mechanisms and Therapeutic Opportunities

Acetaminophen (N-acetyl-para-aminophenol; APAP) overdose is the most common cause of acute liver failure in the Western world, with limited treatment opportunities. For years, research on APAP overdose has been focused on investigating the mechanisms of hepatotoxicity, with limited success in advanc...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Bhushan, Bharat, Apte, Udayan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446224/
https://ncbi.nlm.nih.gov/pubmed/30653954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.12.006
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