Role of Hepatocyte Nuclear Factor 4α (HNF4α) in Cell Proliferation and Cancer

Autor Walesky, Chad, Apte, Udayan
Vydáno v Gene Expr (2015)

Global gene expression changes in liver following hepatocyte nuclear factor 4 alpha deletion in adult mice

Autor Gunewardena, Sumedha, Walesky, Chad, Apte, Udayan
Vydáno v Genom Data (2015)

Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation

Autor Walesky, Chad, Gunewardena, Sumedha, Terwilliger, Ernest F., Edwards, Genea, Borude, Prachi, Apte, Udayan
Vydáno 2013

Hepatocyte Nuclear Factor 4 alpha Deletion Promotes Diethylnitrosamine-induced Hepatocellular Carcinoma in Mice

Autor Walesky, Chad, Edwards, Genea, Borude, Prachi, Gunewardena, Sumedha, O’Neil, Maura, Yoo, Byunggil, Apte, Udayan
Vydáno 2013

Role of Bile Acids in Liver Injury and Regeneration following Acetaminophen Overdose

Autor Bhushan, Bharat, Borude, Prachi, Edwards, Genea, Walesky, Chad, Cleveland, Joshua, Li, Feng, Ma, Xiaochao, Apte, Udayan
Vydáno 2013

Hepatocyte specific deletion of farnesoid X receptor delays, but does not inhibit liver regeneration after partial hepatectomy in mice

Autor Borude, Prachi, Edwards, Genea, Walesky, Chad, Li, Feng, Ma, Xiaochao, Kong, Bo, Guo, Grace L., Apte, Udayan
Vydáno 2012

Pro-Regenerative Signaling after Acetaminophen-Induced Acute Liver Injury in Mice Identified Using a Novel Incremental Dose Model

Autor Bhushan, Bharat, Walesky, Chad, Manley, Michael, Gallagher, Tara, Borude, Prachi, Edwards, Genea, Monga, Satdarshan P.S., Apte, Udayan
Vydáno 2014

Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling

Autor Sun, Lina, Beggs, Kevin, Borude, Prachi, Edwards, Genea, Bhushan, Bharat, Walesky, Chad, Roy, Nairita, Manley, Michael W., Gunewardena, Sumedha, O'Neil, Maura, Li, Hua, Apte, Udayan
Vydáno v Am J Physiol Gastrointest Liver Physiol (2016)

Functional compensation precedes recovery of tissue mass following acute liver injury

Autor Walesky, Chad M., Kolb, Kellie E., Winston, Carolyn L., Henderson, Jake, Kruft, Benjamin, Fleming, Ira, Ko, Sungjin, Monga, Satdarshan P., Mueller, Florian, Apte, Udayan, Shalek, Alex K., Goessling, Wolfram
Vydáno v Nat Commun (2020)

Modulation of O-GlcNAc Levels in the Liver Impacts Acetaminophen-Induced Liver Injury by Affecting Protein Adduct Formation and Glutathione Synthesis

Autor McGreal, Steven R, Bhushan, Bharat, Walesky, Chad, McGill, Mitchell R, Lebofsky, Margitta, Kandel, Sylvie E, Winefield, Robert D, Jaeschke, Hartmut, Zachara, Natasha E, Zhang, Zhen, Tan, Ee Phie, Slawson, Chad, Apte, Udayan
Vydáno v Toxicol Sci (2018)

Mutant IDH inhibits HNF4α to block hepatocyte differentiation and promote biliary cancer

Autor Saha, Supriya K., Parachoniak, Christine A., Ghanta, Krishna S., Fitamant, Julien, Ross, Kenneth N., Najem, Mortada S., Gurumurthy, Sushma, Akbay, Esra A., Sia, Daniela, Cornella, Helena, Miltiadous, Oriana, Walesky, Chad, Deshpande, Vikram, Zhu, Andrew X., Hezel, Aram F., Yen, Katharine, Straley, Kim, Travins, Jeremy, Popovici-Muller, Janeta, Gliser, Camelia, Ferrone, Cristina R., Apte, Udayan, Llovet, Josep M., Wong, Kwok-Kin, Ramaswamy, Sridhar, Bardeesy, Nabeel
Vydáno v Nature (2014)

Advances in cholangiocarcinoma research: report from the third Cholangiocarcinoma Foundation Annual Conference

Autor Abou-Alfa, Ghassan K., Andersen, Jesper B., Chapman, William, Choti, Michael, Forbes, Stuart J., Gores, Gregory J., Hong, Theodore S., Harding, James J., Vander Heiden, Matthew G., Javle, Milind, Kelley, Robin K., Kwong, Lawrence N., Lowery, Maeve, Merrell, Allyson, Miyabe, Katsuyuki, Rhim, Andrew, Saha, Supriya, Sia, Daniela, Tanasanvimon, Suebpong, Venook, Alan, Valle, Juan W., Walesky, Chad, Whetstine, Jonathan, Willenbring, Holger, Zhu, Andrew X., Mayer, Donna, Stanger, Ben Z.
Vydáno v J Gastrointest Oncol (2016)