Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling

Hepatocellular carcinoma (HCC) is the most common hepatic malignancy and the third leading cause of cancer related deaths. Previous studies have implicated bile acids in pathogenesis of HCC, but the mechanisms are not known. We investigated the mechanisms of HCC tumor promotion by bile acids the die...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Sun, Lina, Beggs, Kevin, Borude, Prachi, Edwards, Genea, Bhushan, Bharat, Walesky, Chad, Roy, Nairita, Manley, Michael W., Gunewardena, Sumedha, O'Neil, Maura, Li, Hua, Apte, Udayan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
Témata:
Liver and Biliary Tract Physiology/Pathophysiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967172/
https://ncbi.nlm.nih.gov/pubmed/27151938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00027.2015
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