Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling

Hepatocellular carcinoma (HCC) is the most common hepatic malignancy and the third leading cause of cancer related deaths. Previous studies have implicated bile acids in pathogenesis of HCC, but the mechanisms are not known. We investigated the mechanisms of HCC tumor promotion by bile acids the die...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Sun, Lina, Beggs, Kevin, Borude, Prachi, Edwards, Genea, Bhushan, Bharat, Walesky, Chad, Roy, Nairita, Manley, Michael W., Gunewardena, Sumedha, O'Neil, Maura, Li, Hua, Apte, Udayan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Liver and Biliary Tract Physiology/Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967172/
https://ncbi.nlm.nih.gov/pubmed/27151938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00027.2015
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