Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling

Hepatocellular carcinoma (HCC) is the most common hepatic malignancy and the third leading cause of cancer related deaths. Previous studies have implicated bile acids in pathogenesis of HCC, but the mechanisms are not known. We investigated the mechanisms of HCC tumor promotion by bile acids the die...

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Detalles Bibliográficos
Publicado en:Am J Physiol Gastrointest Liver Physiol
Main Authors: Sun, Lina, Beggs, Kevin, Borude, Prachi, Edwards, Genea, Bhushan, Bharat, Walesky, Chad, Roy, Nairita, Manley, Michael W., Gunewardena, Sumedha, O'Neil, Maura, Li, Hua, Apte, Udayan
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2016
Assuntos:
Liver and Biliary Tract Physiology/Pathophysiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967172/
https://ncbi.nlm.nih.gov/pubmed/27151938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00027.2015
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