Immune exclusion-Wnt/CTNNB1 class predicts resistance to immunotherapies in HCC

Por Pinyol, Roser, Sia, Daniela, Llovet, Josep M
Publicado no Clin Cancer Res (2019)

Cancer Gene Discovery in Hepatocellular Carcinoma

Por Zender, Lars, Villanueva, Augusto, Tovar, Victoria, Sia, Daniela, Chiang, Derek Y., Llovet, Josep M.
Publicado em 2010

Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials

Por Montal, Robert, Andreu-Oller, Carmen, Bassaganyas, Laia, Esteban-Fabró, Roger, Moran, Sebastián, Montironi, Carla, Moeini, Agrin, Pinyol, Roser, Peix, Judit, Cabellos, Laia, Villanueva, Augusto, Sia, Daniela, Mazzaferro, Vincenzo, Esteller, Manel, Llovet, Josep M.
Publicado no Br J Cancer (2019)

An Immune Gene Expression Signature Associated With Development of Human Hepatocellular Carcinoma Identifies Mice That Respond to Chemopreventive Agents

Por Moeini, Agrin, Torrecilla, Sara, Tovar, Victoria, Montironi, Carla, Andreu-Oller, Carmen, Peix, Judit, Higuera, Mónica, Pfister, Dominik, Ramadori, Pierluigi, Pinyol, Roser, Solé, Manel, Heikenwälder, Mathias, Friedman, Scott L., Sia, Daniela, Llovet, Josep M.
Publicado no Gastroenterology (2019)

Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma

Por Bollard, Julien, Miguela, Verónica, Ruiz de Galarreta, Marina, Venkatesh, Anu, Bian, C Billie, Roberto, Mark P, Tovar, Victoria, Sia, Daniela, Molina-Sánchez, Pedro, Nguyen, Christie B, Nakagawa, Shigeki, Llovet, Josep M, Hoshida, Yujin, Lujambio, Amaia
Publicado no Gut (2017)

Gene-expression signature of vascular invasion in hepatocellular carcinoma

Por Mínguez, Beatriz, Hoshida, Yujin, Villanueva, Augusto, Toffanin, Sara, Cabellos, Laia, Thung, Swan, Mandeli, John, Sia, Daniela, April, Craig, Fan, Jian-Bing, Lachenmayer, Anja, Savic, Radoslav, Roayaie, Sasan, Mazzaferro, Vincenzo, Bruix, Jordi, Schwartz, Myron, Friedman, Scott L., Llovet, Josep M.
Publicado em 2011

Tumour initiating cells and IGF/FGF signalling contribute to sorafenib resistance in hepatocellular carcinoma

Por Tovar, Victoria, Cornella, Helena, Moeini, Agrin, Vidal, Samuel, Hoshida, Yujin, Sia, Daniela, Peix, Judit, Cabellos, Laia, Alsinet, Clara, Torrecilla, Sara, Martinez-Quetglas, Iris, Lozano, Juan José, Desbois-Mouthon, Christèle, Solé, Manel, Domingo-Domenech, Josep, Villanueva, Augusto, Llovet, Josep M
Publicado no Gut (2015)

Combining Clinical, Pathology, and Gene Expression Data to Predict Recurrence of Hepatocellular Carcinoma

Por Villanueva, Augusto, Hoshida, Yujin, Battiston, Carlo, Tovar, Victoria, Sia, Daniela, Alsinet, Clara, Cornella, Helena, Liberzon, Arthur, Kobayashi, Masahiro, Kumada, Hiromitsu, Thung, Swan N., Bruix, Jordi, Newell, Philippa, April, Craig, Fan, Jian-Bing, Roayaie, Sasan, Mazzaferro, Vincenzo, Schwartz, Myron E., Llovet, Josep M.
Publicado em 2011

Gender bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR

Por Keng, Vincent W., Sia, Daniela, Sarver, Aaron L., Tschida, Barbara R., Fan, Danhua, Alsinet, Clara, Solé, Manel, Lee, Wai L., Kuka, Timothy P., Moriarity, Branden S., Villanueva, Augusto, Dupuy, Adam J., Riordan, Jesse D., Bell, Jason B., Silverstein, Kevin A.T., Llovet, Josep M., Largaespada, David A.
Publicado em 2012

A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma

Por Labgaa, Ismail, Villacorta-Martin, Carlos, D’Avola, Delia, Craig, Amanda, von Felden, Johann, Martins-Filho, Sebastiao N., Sia, Daniela, Stueck, Ashley, Ward, Stephen C., Fiel, M. Isabel, Mahajan, Milind, Tabrizian, Parissa, Thung, Swan N., Ang, Celina, Friedman, Scott L., Llovet, Josep M., Schwartz, Myron, Villanueva, Augusto
Publicado no Oncogene (2018)

YAP inhibition restores hepatocyte differentiation in advanced HCC leading to tumor regression

Por Fitamant, Julien, Kottakis, Filippos, Benhamouche, Samira, Tian, Helen S., Chuvin, Nicolas, Parachoniak, Christine A., Nagle, Julia M., Perera, Rushika M., Lapouge, Marjorie, Deshpande, Vikram, Zhu, Andrew X., Lai, Albert, Min, Bosun, Hoshida, Yujin, Avruch, Joseph, Sia, Daniela, Campreciós, Genís, McClatchey, Andrea I., Llovet, Josep M., Morrissey, David, Raj, Lakshmi, Bardeesy, Nabeel
Publicado no Cell Rep (2015)

Integrative Molecular Analysis of Intrahepatic Cholangiocarcinoma Reveals 2 Classes That Have Different Outcomes

Por SIA, DANIELA, HOSHIDA, YUJIN, VILLANUEVA, AUGUSTO, ROAYAIE, SASAN, FERRER, JOANA, TABAK, BARBARA, PEIX, JUDIT, SOLE, MANEL, TOVAR, VICTORIA, ALSINET, CLARA, CORNELLA, HELENA, KLOTZLE, BRANDY, FAN, JIAN–BING, COTSOGLOU, CHRISTIAN, THUNG, SWAN N., FUSTER, JOSEP, WAXMAN, SAMUEL, GARCIA–VALDECASAS, JUAN CARLOS, BRUIX, JORDI, SCHWARTZ, MYRON E., BEROUKHIM, RAMEEN, MAZZAFERRO, VINCENZO, LLOVET, JOSEP M.
Publicado em 2013

β-catenin activation promotes immune escape and resistance to anti-PD-1 therapy in hepatocellular carcinoma

Por de Galarreta, Marina Ruiz, Bresnahan, Erin, Molina-Sánchez, Pedro, Lindblad, Katherine E., Maier, Barbara, Sia, Daniela, Puigvehi, Marc, Miguela, Verónica, Casanova-Acebes, María, Dhainaut, Maxime, Villacorta-Martin, Carlos, Singhi, Aatur D., Moghe, Akshata, Von Felden, Johann, Grinspan, Lauren Tal, Wang, Shuang, Kamphorst, Alice O., Monga, Satdarshan P., Brown, Brian D., Villanueva, Augusto, Llovet, Josep M., Merad, Miriam, Lujambio, Amaia
Publicado no Cancer Discov (2019)

Mutant IDH inhibits HNF4α to block hepatocyte differentiation and promote biliary cancer

Por Saha, Supriya K., Parachoniak, Christine A., Ghanta, Krishna S., Fitamant, Julien, Ross, Kenneth N., Najem, Mortada S., Gurumurthy, Sushma, Akbay, Esra A., Sia, Daniela, Cornella, Helena, Miltiadous, Oriana, Walesky, Chad, Deshpande, Vikram, Zhu, Andrew X., Hezel, Aram F., Yen, Katharine, Straley, Kim, Travins, Jeremy, Popovici-Muller, Janeta, Gliser, Camelia, Ferrone, Cristina R., Apte, Udayan, Llovet, Josep M., Wong, Kwok-Kin, Ramaswamy, Sridhar, Bardeesy, Nabeel
Publicado no Nature (2014)

Advances in cholangiocarcinoma research: report from the third Cholangiocarcinoma Foundation Annual Conference

Por Abou-Alfa, Ghassan K., Andersen, Jesper B., Chapman, William, Choti, Michael, Forbes, Stuart J., Gores, Gregory J., Hong, Theodore S., Harding, James J., Vander Heiden, Matthew G., Javle, Milind, Kelley, Robin K., Kwong, Lawrence N., Lowery, Maeve, Merrell, Allyson, Miyabe, Katsuyuki, Rhim, Andrew, Saha, Supriya, Sia, Daniela, Tanasanvimon, Suebpong, Venook, Alan, Valle, Juan W., Walesky, Chad, Whetstine, Jonathan, Willenbring, Holger, Zhu, Andrew X., Mayer, Donna, Stanger, Ben Z.
Publicado no J Gastrointest Oncol (2016)

Molecular predictors of prevention of recurrence in HCC with sorafenib as adjuvant treatment and prognostic factors in the phase 3 STORM trial

Por Pinyol, Roser, Montal, Robert, Bassaganyas, Laia, Sia, Daniela, Takayama, Tadatoshi, Chau, Gar-Yang, Mazzaferro, Vincenzo, Roayaie, Sasan, Lee, Han Chu, Kokudo, Norihiro, Zhang, Zhongyang, Torrecilla, Sara, Moeini, Agrin, Rodriguez-Carunchio, Leonardo, Gane, Edward, Verslype, Chris, Croitoru, Adina Emilia, Cillo, Umberto, de la Mata, Manuel, Lupo, Luigi, Strasser, Simone, Park, Joong-Won, Camps, Jordi, Solé, Manel, Thung, Swan N, Villanueva, Augusto, Pena, Carol, Meinhardt, Gerold, Bruix, Jordi, Llovet, Josep M
Publicado no Gut (2019)

Intratumoral heterogeneity and clonal evolution in liver cancer

Por Losic, Bojan, Craig, Amanda J., Villacorta-Martin, Carlos, Martins-Filho, Sebastiao N., Akers, Nicholas, Chen, Xintong, Ahsen, Mehmet E., von Felden, Johann, Labgaa, Ismail, DʹAvola, Delia, Allette, Kimaada, Lira, Sergio A., Furtado, Glaucia C., Garcia-Lezana, Teresa, Restrepo, Paula, Stueck, Ashley, Ward, Stephen C., Fiel, Maria I., Hiotis, Spiros P., Gunasekaran, Ganesh, Sia, Daniela, Schadt, Eric E., Sebra, Robert, Schwartz, Myron, Llovet, Josep M., Thung, Swan, Stolovitzky, Gustavo, Villanueva, Augusto
Publicado no Nat Commun (2020)