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Immune exclusion-Wnt/CTNNB1 class predicts resistance to immunotherapies in HCC

Next generation sequencing has provided information on actionable targets and biomarkers of response in oncology. In HCC, Wnt/CTNNB1 mutations characterize the immune excluded class (cold tumors) and might represent the biomarkers predicting resistance to immune checkpoint inhibitors. Large-scale va...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Pinyol, Roser, Sia, Daniela, Llovet, Josep M
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445700/
https://ncbi.nlm.nih.gov/pubmed/30617138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3778
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