An Immune Gene Expression Signature Associated With Development of Human Hepatocellular Carcinoma Identifies Mice That Respond to Chemopreventive Agents

BACKGROUND & AIMS: Cirrhosis and chronic inflammation precede development of hepatocellular carcinoma (HCC) in approximately 80% of cases. We investigated immune-related gene expression patterns in liver tissues surrounding early-stage HCCs and chemopreventive agents that might alter these patte...

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Publié dans:Gastroenterology
Auteurs principaux: Moeini, Agrin, Torrecilla, Sara, Tovar, Victoria, Montironi, Carla, Andreu-Oller, Carmen, Peix, Judit, Higuera, Mónica, Pfister, Dominik, Ramadori, Pierluigi, Pinyol, Roser, Solé, Manel, Heikenwälder, Mathias, Friedman, Scott L., Sia, Daniela, Llovet, Josep M.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815707/
https://ncbi.nlm.nih.gov/pubmed/31344396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.07.028
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