A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma

Cellular components of solid tumors including DNA are released into the bloodstream, but data on circulating-free DNA (cfDNA) in hepatocellular carcinoma (HCC) are still scarce. This study aimed at analyzing mutations in cfDNA and their correlation with tissue mutations in patients with HCC. We incl...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Labgaa, Ismail, Villacorta-Martin, Carlos, D’Avola, Delia, Craig, Amanda, von Felden, Johann, Martins-Filho, Sebastiao N., Sia, Daniela, Stueck, Ashley, Ward, Stephen C., Fiel, M. Isabel, Mahajan, Milind, Tabrizian, Parissa, Thung, Swan N., Ang, Celina, Friedman, Scott L., Llovet, Josep M., Schwartz, Myron, Villanueva, Augusto
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035113/
https://ncbi.nlm.nih.gov/pubmed/29628508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0206-3
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