Transcriptomic characterization of cancer-testis antigens identifies MAGEA3 as a driver of tumor progression in hepatocellular carcinoma

Cancer testis antigens (CTAs) are an extensive gene family with a unique expression pattern restricted to germ cells, but aberrantly reactivated in cancer tissues. Studies indicate that the expression (or re-expression) of CTAs within the MAGE-A family is common in hepatocellular carcinoma (HCC). Ho...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Craig, Amanda J., Garcia-Lezana, Teresa, Ruiz de Galarreta, Marina, Villacorta-Martin, Carlos, Kozlova, Edgar G., Martins-Filho, Sebastiao N., von Felden, Johann, Ahsen, Mehmet Eren, Bresnahan, Erin, Hernandez-Meza, Gabriela, Labgaa, Ismail, D’Avola, Delia, Schwartz, Myron, Llovet, Josep M., Sia, Daniela, Thung, Swan, Losic, Bojan, Lujambio, Amaia, Villanueva, Augusto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224860/
https://ncbi.nlm.nih.gov/pubmed/34166362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009589
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