Inactivation of a class A and a class C β-lactamase by 6β-(hydroxymethyl)penicillanic acid sulfone

β-Lactamase inhibitors (clavulanic acid, sulbactam, and tazobactam) contribute significantly to the longevity of the β-lactam antibiotics used to treat serious infections. In the quest to design more potent compounds and to understand the mechanism of action of known inhibitors, 6β-(hydroxymethyl)pe...

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Detalhes bibliográficos
Main Authors: Papp-Wallace, Krisztina M., Bethel, Christopher R., Gootz, Thomas D., Shang, Wenchi, Stroh, Justin, Lau, William, McLeod, Dale, Price, Loren, Marfat, Anthony, Distler, Anne, Drawz, Sarah M., Chen, Hansong, Harry, Emily, Nottingham, Micheal, Carey, Paul R., Buynak, John D., Bonomo, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319978/
https://ncbi.nlm.nih.gov/pubmed/22155308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.11.015
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