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Inactivation of a class A and a class C β-lactamase by 6β-(hydroxymethyl)penicillanic acid sulfone

β-Lactamase inhibitors (clavulanic acid, sulbactam, and tazobactam) contribute significantly to the longevity of the β-lactam antibiotics used to treat serious infections. In the quest to design more potent compounds and to understand the mechanism of action of known inhibitors, 6β-(hydroxymethyl)pe...

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書誌詳細
主要な著者: Papp-Wallace, Krisztina M., Bethel, Christopher R., Gootz, Thomas D., Shang, Wenchi, Stroh, Justin, Lau, William, McLeod, Dale, Price, Loren, Marfat, Anthony, Distler, Anne, Drawz, Sarah M., Chen, Hansong, Harry, Emily, Nottingham, Micheal, Carey, Paul R., Buynak, John D., Bonomo, Robert A.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319978/
https://ncbi.nlm.nih.gov/pubmed/22155308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.11.015
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