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LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48
OBJECTIVES: Carbapenemases are the most important mechanism responsible for carbapenem resistance in Enterobacteriaceae. Among carbapenemases, OXA-48 presents unique challenges as it is resistant to β-lactam inhibitors. Here, we test the capacity of the compound LN-1-255, a 6-alkylidene-2′-substitut...
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| 發表在: | J Antimicrob Chemother |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4954921/ https://ncbi.nlm.nih.gov/pubmed/27125555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw105 |
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