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Inhibitor Resistance in the KPC-2 β-Lactamase, a Preeminent Property of This Class A β-Lactamase

As resistance determinants, KPC β-lactamases demonstrate a wide substrate spectrum that includes carbapenems, oxyimino-cephalosporins, and cephamycins. In addition, clinical strains harboring KPC-type β-lactamases are often identified as resistant to standard β-lactam-β-lactamase inhibitor combinati...

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Detalhes bibliográficos
Main Authors: Papp-Wallace, Krisztina M., Bethel, Christopher R., Distler, Anne M., Kasuboski, Courtney, Taracila, Magdalena, Bonomo, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812178/
https://ncbi.nlm.nih.gov/pubmed/20008772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00693-09
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